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ANSWERED September 2009:
A multiple disk tray approach is needed in this situation. You do not want to put the Office files on the fastest and most expensive disks, however the SQL data does require high performance. A fast SCSI disk tray configured as RAID 10 will give the best SQL performance, while a secondary disk tray with SATA drives configured as RAID 5 will give resilience at a much reduced cost.
With some storage-area networks it is possible to move data between these drive sets using an automated data tiering function based on user-defined file access rules. You may also be able to pin data by volume into specific disk areas so you could, for example, use the fastest disk tray for the SQL data. RAID 10 uses a stripe and mirror approach that is fast and resilient. RAID 5 stripes disks with parity providing resilience against disk failure with a one to three disk overhead.
For more information, read "RAID levels explained"
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